The Journal

Explore our latest articles, insights, and stories from the PEPAX team.

hydrogen water and depression | PEPAX Supplements
JUN 06, 2026 Hydrogen Water and Mood: The Oxidative-Stress Hypothesis of Depression

hydrogen water and depressionA growing body of research frames depression partly as a neuroinflammatory, oxidative-stress condition. Animal models and a handful of...

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magnesium and growth hormone | PEPAX Supplements
JUN 06, 2026 Magnesium, Growth Hormone, and Recovery: The Overnight Repair Connection

magnesium and growth hormoneMost growth hormone is released during deep slow-wave sleep — precisely the sleep stage magnesium helps protect. By deepening...

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VO2 max and longevity | PEPAX Supplements
JUN 06, 2026 VO2 Max and Longevity: Why Cardiorespiratory Fitness Predicts Lifespan

VO2 max and longevityVO2 max — the ceiling on how much oxygen your body can use — is one of the strongest...

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hydrogen water and migraine | PEPAX Supplements
JUN 06, 2026 Hydrogen Water and Migraine: The Oxidative-Stress and Inflammation Hypothesis

hydrogen water and migraineMigraine involves neurogenic inflammation, oxidative stress, and cortical hyperexcitability. Hydrogen's antioxidant and anti-inflammatory actions make it a theoretically interesting...

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magnesium and nerve function | PEPAX Supplements
JUN 06, 2026 Magnesium and Nerve Function: The Mineral's Role in Neuropathy and Nerve Excitability

magnesium and nerve functionMagnesium gates the NMDA receptor and stabilizes nerve-membrane excitability — when it's low, nerves fire too easily, producing tingling,...

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NMN and endothelial function | PEPAX Supplements
JUN 06, 2026 NMN and Endothelial Function: How NAD+ Supports the Lining of Your Blood Vessels

NMN and endothelial functionThe endothelium — the single-cell lining of every vessel — is where vascular aging begins, and its nitric-oxide output...

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hydrogen water and wound healing | PEPAX Supplements
JUN 06, 2026 Hydrogen Water and Wound Healing: The Oxidative-Stress Angle on Skin Repair

hydrogen water and wound healingWound repair stalls when oxidative stress and chronic inflammation dominate the healing environment — the situation in diabetic...

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magnesium and dopamine | PEPAX Supplements
JUN 06, 2026 Magnesium and Dopamine: The Mineral's Role in Motivation and Reward

magnesium and dopamineMagnesium and vitamin B6 are both cofactors in the synthesis and regulation of dopamine. Deficiency is linked to low motivation,...

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berberine and metabolic aging | PEPAX Supplements
JUN 06, 2026 Berberine and Metabolic Aging: 'Nature's Metformin' Under the Evidence Microscope

berberine and metabolic agingBerberine activates AMPK — the same energy-sensing pathway as metformin and exercise — and has solid human data for...

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