The Journal

Explore our latest articles, insights, and stories from the PEPAX team.

magnesium astragalus combination | PEPAX Supplements
MAY 27, 2026 Magnesium and Astragalus Together: Evidence for This Adaptogen Combination

magnesium astragalus combinationMagnesium and astragalus address complementary aspects of stress physiology — magnesium modulates the HPA axis and GABA receptors while astragalus...

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magnesium and inflammation | PEPAX Supplements
MAY 27, 2026 Magnesium and Inflammation: The Link Between Deficiency and CRP Levels

magnesium and inflammationC-reactive protein (CRP), a key inflammatory biomarker, is consistently elevated in people with low dietary magnesium intake. Meta-analyses demonstrate that...

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hallmarks of aging supplements | PEPAX Supplements
MAY 27, 2026 The 9 Hallmarks of Aging: What Supplements Can and Cannot Address

hallmarks of aging supplementsThe 2013 López-Otín framework identified 9 hallmarks of aging including genomic instability, telomere attrition, mitochondrial dysfunction, and chronic inflammation....

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magnesium and ADHD | PEPAX Supplements
MAY 26, 2026 Magnesium and ADHD: What Research Shows About Focus, Hyperactivity, and Minerals

magnesium and ADHDChildren and adults with ADHD show higher rates of magnesium deficiency than the general population. Observational studies and small RCTs...

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vitamin D3 optimal levels | PEPAX Supplements
MAY 26, 2026 Vitamin D3 Optimal Levels: Why Most People Need More Than the RDA

vitamin D3 optimal levelsThe official RDA for Vitamin D3 (600–800 IU) targets deficiency prevention, not optimal function. Researchers studying immune function, bone...

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NMN and immune function | PEPAX Supplements
MAY 26, 2026 NMN and Immune Function: How NAD+ Supports T Cell Activity and Inflammation

NMN and immune functionImmune cells — particularly T cells and macrophages — are highly NAD+-dependent. NAD+ depletion impairs immune cell proliferation, cytokine...

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magnesium and blood sugar | PEPAX Supplements
MAY 26, 2026 Magnesium and Blood Sugar: Evidence on Insulin Sensitivity and Type 2 Diabetes Risk

magnesium and blood sugarMagnesium is a cofactor in over 300 enzymatic reactions, including glucose metabolism and insulin receptor signaling. Meta-analyses show that...

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best time to take magnesium | PEPAX Supplements
MAY 26, 2026 Best Time to Take Magnesium: Morning vs Night, With Food or Without

best time to take magnesiumMagnesium timing depends on your primary goal: sleep and anxiety benefits favor evening dosing 1–2 hours before bed,...

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how long does NMN take to work | PEPAX Supplements
MAY 26, 2026 How Long Does NMN Take to Work? Clinical Timeline for NAD+ Effects

how long does NMN take to workBlood NAD+ levels rise within hours of NMN dosing in human trials, but functional benefits —...

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